How Fast Does Mesothelioma Spread? Mesothelioma is one of the most aggressive forms of cancer and just like most cancers, it’s progressive. This means that as the disease advances, cancerous cells begin to spread to other parts of the body. The cancer progresses through stages 1, 2, 3, and 4 and eventually spreads or metastasizes to other parts of the body. This is what makes it one of the most aggressive and deadliest forms of cancer. “Once mesothelioma tumors have formed, the microscopic cells that make up the tumor can spread throughout the body. These cells form new tumors in the body. At this point, a patient’s disease is said to be metastatic.” How Fast Does Mesothelioma Spread? Generally, mesothelioma progresses quickly through the stages and to metastasis. However, how fast the cancer spreads depends on a number of factors including the cell-types, location, the age of patient, general health, and treatment. Cell-types Mesothelioma tumors consist of three main c...